How Does Cancer Produce Signs and Symptoms?
A cancer may cause generalized symptoms such as fever, fatigue, or weight loss. This may be caused by cancer cells releasing substances that change the body’s metabolism. Or the cancer may cause the immune system to react in ways that produce these symptoms.
Sometimes, cancer cells release substances into the bloodstream that cause symptoms not generally thought to result from cancers. For example, some cancers of the pancreas can release substances which cause blood clots to develop in veins of the legs. Some lung cancers produce hormone-like substances that affect blood calcium levels, affecting nerves and muscles and causing weakness and dizziness.
How are Signs and Symptoms Helpful?
Treatment is most successful when the cancer is found as early as possible. Finding cancer early usually means it can be treated while it is still small and is less likely to have spread to other parts of the body. Usually, this means a better chance for a cure, especially if initial treatment is to be surgery.
A good example of the importance of detecting cancer early is melanoma skin cancer. It is easily removed if has not yet grown deeply into the skin, and the 5-year survival rate (percentage of people living at least 5 years after diagnosis) at this stage is nearly 100%. But once melanoma has spread to other parts of the body, the survival rate drops dramatically.
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